Kidney Cancer Guide: Treatment ABX-EGF

Treatments

Treatment Category Profile

Treatment Name: ABX-EGF Known as:

Also Known As: ABX-EGF

Treatment Type: Immunotherapy Status: FDA Approved (phase II)

Tumor cells that overexpress ("EGFr") on their surface often depend on EGFr's activation for growth. EGFr is overexpressed in kidney cancer, among others, and the belief is that by blocking the ability of EGF and TGFa to bind with EGFr may offer a treatment.

Articles related to this Treatment

1 ASCO: Experimental Epidermal Growth Factor Receptor Inhibitor Shows Responses in Renal Cell Cancer Doctor's Guide May 22, 2002

2 Abgenix, Inc. CEUT May 22, 2002

3 Preliminary Phase 2 Data Suggest ABX-EGF Has Single-Agent Anti-Tumor Activity in Advanced Kidney Cancer Yahoo! Finance May 21, 2002

4 Abgenix Says Drug Is Effective Against Kidney Cancer thestreet.com May 21, 2002

5 ABX-EGF for NSCLC Oncology Week in Review Aug 2, 2001

6 Tolerability Demonstrated by ABX-EGF as Monotherapy in Advanced Cancers Abgenix.com May 14, 2001

7 ABX-EGF enters phase-2 Oncology Week in Review Apr 19, 2001

Treatment Name:	ABX-EGF	Known as: Also Known As:	ABX-EGF
Treatment Type:	Immunotherapy	Status:	FDA Approved (phase II)
Tumor cells that overexpress ("EGFr") on their surface often depend on EGFr's activation for growth. EGFr is overexpressed in kidney cancer, among others, and the belief is that by blocking the ability of EGF and TGFa to bind with EGFr may offer a treatment.