Kidney Cancer Guide: Treatment Endostatin

Treatments

Treatment Category Profile

Treatment Name: Endostatin Known as:

Also Known As: Endostatin

Treatment Type: Anti-Angiogenesis Status: FDA Approved (phase I)

Endostatin is a naturally occurring enzyme which inhibits angiogenesis. In theory it could starve tumors without attacking them directly, by disabling expansion of the blood supply. Endostatin showed quite promising results in mouse studies, however human trials have thus far achieved only modest success rates.

Articles related to this Treatment

1 Endostatin's Luster Dims, EntreMed Slides PSA Rising Magazine Nov 14, 2002

2 Hopes in cancer drug dashed JSOnline May 25, 2002

3 Endostatin phase-1/2 begins Oncology Week in Review Jul 12, 2001

4 EntreMed's Endostatin Appears Safe, Well-Tolerated in Phase I Trials Reuters Medical News Nov 10, 2000

5 Endostatin Makes Modest Debut Oncology Week in Review Nov 9, 2000

6 Drug not as potent as many hoped Boston Globe Nov 7, 2000

7 In 1st trials, cancer drug Endostatin disappoints Chicago Tribune May 14, 2000

8 No triumphs seen yet in cancer drug Boston Globe May 11, 2000

9 Little Results in Cancer Drug Tests Yahoo News May 11, 2000

10 TRIAL SUCCESS IN THE DETAILS, FOLKMAN SAYS Chicago Tribune Oct 17, 1999

Treatment Name:	Endostatin	Known as: Also Known As:	Endostatin
Treatment Type:	Anti-Angiogenesis	Status:	FDA Approved (phase I)
Endostatin is a naturally occurring enzyme which inhibits angiogenesis. In theory it could starve tumors without attacking them directly, by disabling expansion of the blood supply. Endostatin showed quite promising results in mouse studies, however human trials have thus far achieved only modest success rates.